Kutcher subsequently appeared in more romantic comedies, including Guess Who (2005), A Lot Like Love (2005), What Happens in Vegas (2008), and No Strings Attached (2011).
From 2011 to 2015, he starred as Walden Schmidt on the CBS sitcom Two and a Half Men.
He made his film debut in the romantic comedy Coming Soon and became known by audiences in the comedy film Dude, Where's My Car? In 2003, Kutcher appeared in romantic comedies Just Married and My Boss's Daughter and, the same year, he created, produced, and hosted Punk'd which aired on MTV for five seasons until its revival in 2012.
In 2004, Kutcher starred in the lead role of the psychological film The Butterfly Effect and gained public recognition.
He has said that he "didn't want to come home and find more bad news" about his brother, stating, "I kept myself so busy that I didn't allow myself to feel." Kutcher stated that, when he was 13, he contemplated committing suicide to save his brother's life with a heart transplant; when he told his father he was considering jumping from a Cedar Rapids hospital balcony, his father dissuaded him from doing so shortly before doctors announced that a transplant had become available from an accident victim in another state.